Polymerase (DNA Directed) kappa (POLK) (N-Term) Peptide
POLK
Reactivité: Humain
Hôte: Synthetic
BP, WB
N° du produit ABIN981953
Aperçu rapide pour Polymerase (DNA Directed) kappa (POLK) (N-Term) Peptide (ABIN981953)
Antigène
POLK
(Polymerase (DNA Directed) kappa (POLK))
Origine
Humain
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
-
-
Protein Region
- N-Term
-
Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-POLK antibody (Catalog #: ARP48792_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
-
Purification
- Purified
-
-
-
-
Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
-
Restrictions
- For Research Use only
-
-
-
Format
- Lyophilized
-
Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
-
Concentration
- 1 mg/mL
-
Buffer
- Final peptide concentration is 1 mg/mL in PBS.
-
Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
-
Stock
- -20 °C
-
Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
-
- POLK (Polymerase (DNA Directed) kappa (POLK))
-
Sujet
-
POLK belongs to the DNA polymerase type-Y family. It contains 2 Rad18-type zinc fingers and 1 umuC domain. POLK is a DNA polymerase specifically involved in DNA repair. It plays an important role in translesion synthesis, where the normal high-fidelity DNA polymerases cannot proceed and DNA synthesis stalls. Depending on the context, it inserts the correct base, but causes frequent base transitions, transversions and frameshifts. It lacks 3'-5' proofreading exonuclease activity. POLK forms a Schiff base with 5'-deoxyribose phosphate at abasic sites, but does not have lyase activity.
Alias Symbols: DINB1, DINP, POLQ
Protein Interaction Partner: REV1,REV1
Protein Size: 870 -
Poids moléculaire
- 99 kDa
-
ID gène
- 51426
-
NCBI Accession
- NM_016218, NP_057302
-
UniProt
- Q9UBT6
Antigène
-
Vous êtes ici:
